Everything about Cholic Acid totally explained
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Cholic acid is a
bile acid, a white crystalline substance insoluble in water (soluble in
alcohol and
acetic acid), with a melting point of 200-201 °C. Salts of cholic acid are called
cholates. Cholic acid, along with
chenodeoxycholic acid, is one of two major
bile acids produced by the
liver where it's synthesized from
cholesterol. Of the two major bile acids, cholate derivatives represent approximately eighty percent of all bile acids. These derivatives are made from cholyl-CoA which forms a
conjugate with either
glycine, or
taurine, yielding
glycocholic and
taurocholic acid respectively.
Cholic acid and
chenodeoxycholic acid are the most important human bile acids. Some other mammals synthesize predominantly
deoxycholic acid.
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